Drug discovery today
Next-generation drug conjugates for breast cancer: Clinical prospects and mechanism-based strategies to overcome resistance.
Monong Zhao, Wenjing Liu, Wenjia Lu, Zhiyu Li, Hongxi Wu
Published: 202610.1016/j.drudis.2026.104599
Abstract
Antibody-drug conjugates (ADCs) have revolutionized breast cancer (BC) therapy, yet their efficacy is limited by resistance. With advances in ADC technology, broader paradigms of next-generation drug conjugates have emerged. For BC treatment, emergin…
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