Drug discovery today
Decoding protein kinases in autophagy with small-molecule modulators for cancer therapy.
Mengqiao Chen, Xiangyu Fu, Huiping Wang, Xinyi Qi, Leilei Fu
Published: 202510.1016/j.drudis.2025.104565
Abstract
Autophagy is an intracellular degradation and recycling mechanism, crucial for maintaining cellular homeostasis. In recent years, the dual role of protein kinases in autophagy has gradually been elucidated. Designing small-molecule compounds to regul…
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