DNA repairHumansDNA DamageDNA RepairSignal TransductionPoly Adenosine Diphosphate Ribose
PARP enzyme synthesis of protein-free poly(ADP-ribose): Implications for DNA damage signaling and repair.
Marie-France Langelier, John M Pascal
Published: 202510.1016/j.dnarep.2025.103898
Abstract
Poly(ADP-ribose) or PAR is a versatile signaling molecule with a broad impact on human biology. PAR is a prominent indicator of cellular DNA damage and genomic transactions such as replication and transcription. Canonically, human PARP enzymes create…
Preview only. Read the full abstract at the source