Drug metabolism and disposition: the biological fate of chemicalsHumansParkinson DiseaseGastrointestinal MicrobiomeCytochrome P-450 Enzyme SystemAnimals
The role of cytochrome P450 and gut microbiome in drug metabolism: Insights into Parkinson disease treatment.
Sindduja Muthukumar, Harysh Winster Suresh Babu, Anto George, Brij Mohan Maurya, Iyer Mahalaxmi, Mukesh Kumar Yadav, Dibbanti HariKrishna Reddy, Arvinder Wander, Arul Narayanasamy, Raja Ganesan, Vikas Lakhanpal, Balachandar Vellingiri
Published: 202510.1016/j.dmd.2025.100166
Abstract
Parkinson disease (PD) is a complex neurodegenerative condition marked by progressive motor and nonmotor symptoms. Cytochrome P450 (P450) enzymes, notably those from the CYP1 and CYP2 families, are increasingly recognized as significant factors in th…
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