A dataset on the phylogeny of Mycobacterium avium subsp. paratuberculosis isolated from patients in a referral gastrointestinal diseases centre in the Sudan.

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of paratuberculosis in animals, a disease characterized by chronic intestinal inflammation. MAP has also been detected in patients with Crohn's disease and other illnesses, raising concerns about its potential public health implications. Recently, we isolated MAP from tissue and stool samples of human patients with gastrointestinal complaints for the first time in the Sudan. This dataset aimed at investigating the phylogenetic relationships of these Sudanese MAP human isolates to local animal MAP isolates and MAP strains worldwide. DNA was extracted from MAP cultures of patient tissues and stools, partially amplified for the MAP IS1311 gene using nested PCR, and then sequenced. High-quality sequences of 13 isolates (2 stool and 11 tissue isolates) together with corresponding sequences of Sudanese MAP animal isolates and of MAP strains from other countries were used to construct a phylogenetic tree. The phylogeny tree showed that the Sudanese human MAP isolates are closely related to the Sudanese animal isolates and to the MAP S-type (Sheep-type) strains from other countries including Australia, the USA, Germany, and New Zealand.