Developmental cellMicrogliaAnimalsCell AdhesionIntegrinsCentral Nervous System
Integrin-mediated adhesion drives microglial entry into the developing CNS.
Fanny Jaudon, Lorenzo A Cingolani
Published: 202610.1016/j.devcel.2025.12.006
Abstract
In this issue of Developmental Cell, Petry et al. show that early microglial progenitors infiltrate the embryonic CNS via an extracellular matrix (ECM)-rich pial route requiring talin-1-dependent integrin activation. This work revises long-standing v…
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