Developmental cellGlioblastomaNeoplastic Stem CellsHumansInflammationTumor Microenvironment
How glioblastoma stem cells turn inflammatory cues into tumor growth and immune suppression.
Wenhui Chen, Yanjie Shen, Guangshuai Jia
Published: 202510.1016/j.devcel.2025.06.011
Abstract
Chronic inflammation shapes the tumor microenvironment and influences cancer stem cell behavior. In this issue of Developmental Cell, Gu et al. identify TNFAIP6 as a key responder to tumor necrosis factor alpha (TNF-α) that promotes self-renewal of g…
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