Cytokine
Sennoside A alleviates fungal keratitis by modulating inflammation and immune responses through the caspase-1/GSDMD pathway.
Mengzhu Liu, Nan Jiang, Shiqi Song, Qiang Xu, Ling Wang, Fenglei Wang, Xiaomei Wan, Xiaoyan Sun, Chengye Che
Published: 202610.1016/j.cyto.2026.157120
Abstract
PURPOSE: This study was designed to systematically investigate the therapeutic efficacy and mechanistic underpinnings of the natural plant-derived anthraquinone glycoside, sennoside A (SA), in fungal keratitis. METHODS: We rigorously assessed the saf…
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