CytokineAnimalsMiceMacrophagesUbiquitin ThiolesteraseRAW 264.7 Cells
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Mingming Zhao, Junjie Shi, Xinqi Wei, Wenze Tian, Yuee Chen
Published: 202610.1016/j.cyto.2025.157079
Abstract
Macrophages are key immune cells that regulate the body's immune response by promoting the release of inflammatory cytokines upon recognition of both endogenous and exogenous pathogens. USP14, a critical deubiquitinase, plays a vital role in various…
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