CytokineHumansSepsisMaleFemaleRespiratory Distress Syndrome
Association of the soluble form of the endothelial Tie2 receptor with organ failure and mortality in patients with sepsis and ARDS.
Nicolas J Wegmann, Dorothea M Heuberger, Gabor Kadler, Benjamin Seeliger, Thorben Pape, Klaus Stahl, Mattia M Müller, Sascha David
Published: 202510.1016/j.cyto.2025.157062
Abstract
INTRODUCTION: Tie2 is an endothelial surface receptor critically involved in angiogenesis, cell-integrity, and survival. During inflammatory disorders such as sepsis and ARDS, the receptor is shed from the endothelial surface, contributing to a reduc…
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