Cancer treatment and research communications
Characterization of POU2F3-expressing large cell neuroendocrine carcinoma of the lung: A comprehensive analysis of morphology, immunohistochemistry, and genomic alterations.
Ryota Matsuoka, Kei Asayama, Tomoki Nakagawa, Yoshihiko Murata, Ayako Suzuki, Yutaka Suzuki, Naohiro Kobayashi, Yukio Sato, Nobuyuki Hizawa, Hiroyoshi Tsubochi, Shunsuke Endo, Koichi Hagiwara, Toshiro Niki, Noriyoshi Fukushima, Kentaro Inamura
Published: 202610.1016/j.ctarc.2026.101113
Abstract
Large cell neuroendocrine carcinoma (LCNEC) is a neuroendocrine carcinoma (NEC) of the lung that is characterized by its heterogeneous morphology, diverse immunophenotypes, and complex genomic profiles. Among LCNECs, a subset expressing the transcrip…
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