Cancer treatment and research communicationsHumansMaleFemaleTumor Suppressor Protein p53Proto-Oncogene Proteins p21(ras)
Clinical significance of concurrent TP53 mutations in KRAS-mutant invasive mucinous adenocarcinoma patients undergoing curative-intent lung surgery.
Dong Woog Yoon, Soohyun Hwang, Boram Lee, Yeong Jeong Jeon, Junghee Lee, Dong Wook Shin, Byeong-Ho Jeong, Seong Yong Park, Hong Kwan Kim, Yong Soo Choi, Jong Ho Cho
Published: 202510.1016/j.ctarc.2025.101014
Abstract
BACKGROUND: Invasive mucinous adenocarcinoma (IMA) is genetically distinct from non-mucinous adenocarcinoma, commonly characterized by KRAS mutations. However, studies exploring molecular co-alterations alongside KRAS mutations in IMA remain limited.…
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