Cancer treatment and research communicationsFemaleHumansAdenomatous Polyposis ColiAnaplastic Lymphoma KinaseGenetic Predisposition to Disease
Assessing the pathogenicity of a variant of uncertain significance in the ALK gene in right-sided colon polyposis.
Zeinab Aliyari Serej, Maryam Naghinejad, Sepideh Parvizpour, Mortaza Raeisi, Vahid Jafarlou, Abbas Ebrahimi Kalan, Sima Mansoori Derakhshan, Mohammad Taheri
Published: 202510.1016/j.ctarc.2025.101010
Abstract
Colorectal cancer (CRC) is the third most common cancer worldwide. Generally, Familial Adenomatous Polyposis (FAP) accounts for about 1 % to 2 % of all colorectal cancer cases. Mutations in the APC gene, inherited in an autosomal dominant manner, and…
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