Critical reviews in oncology/hematologyHumansOncolytic VirotherapyNeoplasmsAnimalsOncolytic Viruses
Oncolytic virotherapy: Molecular mechanisms, delivery strategies, and translational insights.
Talal Jamil Qazi, Alanne Tenório Nunes, Pedro Luiz Porfirio Xavier, Heidge Fukumasu
Published: 202610.1016/j.critrevonc.2025.105061
Abstract
Despite major gains with immunotherapy, many tumors remain non-responsive because of poor antigen release and a suppressive tumor microenvironment (TME). Oncolytic virotherapy (OVT) directly lyses cancer cells and secondarily inflames the TME via imm…
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