Critical reviews in oncology/hematologyHumansReceptorsChimeric AntigenImmunotherapyAdoptive
Chimeric antigen receptor-based cellular therapy for T-cell malignancies.
Sile Li, Yuanxin Li, Man Yan Hui, Asif Rashid, Hong Kee Tan, Shing Chan, Wilson Yau Ki Chan, Kee See Lam, Wenwei Tu, Wing Leung
Published: 202610.1016/j.critrevonc.2025.105044
Abstract
Chimeric antigen receptor (CAR) T-cell therapy utilizes synthetic biology techniques to engineer T cells to specifically target tumor cells using most commonly single-chain variable fragments (scFvs) to recognize tumor-associated antigens, which has…
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