Critical reviews in oncology/hematologyHumansCarcinomaRenal CellKidney NeoplasmsImmune Checkpoint Inhibitors
Chromophobe renal cell carcinoma: Emerging vulnerabilities as a promise for a new therapeutic landscape.
Samer Salem, Michel Alchoueiry, Wenxin Xu, Elizabeth P Henske
Published: 202510.1016/j.critrevonc.2025.104985
Abstract
Chromophobe renal cell carcinoma (ChRCC) is a rare tumor and the third most common subtype of renal cell carcinoma and is characterized by low tumor mutational burden, mitochondrial abnormalities, and distinct metabolic dependencies. Historically gro…
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