Current opinion in virology
Human autoantibodies against type I interferons in severe viral disease.
Kevin Groen, Benjamin G Hale
Published: 202610.1016/j.coviro.2026.101511
Abstract
Type I interferons (IFN-Is) are critical antiviral cytokines that restrict viral replication and limit viral disease. A remarkable recent discovery is that human autoantibodies (autoAbs) neutralizing the activities of IFN-Is phenocopy inborn errors o…
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