Computers in biology and medicineCTLA-4 AntigenHumansPolymorphismSingle NucleotideB7-1 Antigen
Demystifying the implications of disease-susceptible missense SNPs within CTLA-4 ligand binding domain and its interaction towards B7-1 protein complex: Bioinformatics-driven evidence.
V Shamala, S Preethi, V Hemamalini, S Asha Devi
Published: 202610.1016/j.compbiomed.2026.111459
Abstract
Alteration of a nucleotide within a triplet codon results in substitution of a different amino acid in the protein sequence, collectively termed as missense or non-synonymous Single-Nucleotide Polymorphisms (nsSNPs). Cytoplasmic T Lymphocytes Antigen…
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