Computers in biology and medicineEndoplasmic Reticulum StressHumansAnimalsRatsPulmonary Arterial Hypertension
Mechanistic study of ANXA3-mediated endoplasmic reticulum stress promoting M1 macrophage polarization in pulmonary arterial hypertension based on bioinformatics and nine machine learning algorithms.
Chen Xing, Liang Limei, Xu Liping, Li Lixiang, Yang Liulin, Liang Guizi, Xie Dongwei, Liao Juan, Meng Hui, Deng Yan
Published: 202510.1016/j.compbiomed.2025.111215
Abstract
BACKGROUND: Endoplasmic reticulum stress (ERS) plays a critical role in inflammation-related disorders, but its immunoregulatory mechanisms in pulmonary arterial hypertension (PAH) remain unclear. This study aimed to identify key ERS-associated genes…
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