Computational biology and chemistryDrug DiscoveryMolecular StructureDeep LearningPharmaceutical PreparationsHumans
SSHF-DTI: Leveraging structural similarity and hierarchical features through a fusion network for drug-target interaction prediction.
Yuxiao Zhang, Chengping Zhao
Published: 202610.1016/j.compbiolchem.2025.108853
Abstract
Predicting drug-target interactions (DTI) and binding affinities (DTA) is essential for drug discovery, but experimental methods remain costly and time-consuming. While deep learning approaches have improved prediction performance, many existing mode…
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