Computational biology and chemistryHumansOxidative StressNasal PolypsSinusitisComputational Biology
Integrative bioinformatics analysis reveals that microplastics promote chronic rhinosinusitis with nasal polyps through NOXO1-mediated oxidative stress and myoepithelial cell reprogramming.
Yun Gao, Lejun Li, Yixing Huang, Xudong Zhao, Yaoshu Teng
Published: 202610.1016/j.compbiolchem.2025.108843
Abstract
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex inflammatory disease whose environmental pathogenic factors remain unclear. Microplastics, as emerging environmental pollutants, have been confirmed to deposit in the respiratory tract an…
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