Computational biology and chemistryVascular Endothelial Growth Factor AHumansMacular DegenerationMolecular Docking SimulationRanibizumab
Computational modeling of anti-VEGFA drug interactions with VEGF-A: Insights into therapeutic strategies for neovascular AMD.
Ángel Parra-Sánchez, Alba Román-Vallina, Eduardo Fernández, Gema Martínez-Navarrete
Published: 202610.1016/j.compbiolchem.2025.108788
Abstract
Vascular endothelial growth factor A (VEGF-A) is the main driver of pathological angiogenesis and represents the primary therapeutic target in neovascular age-related macular degeneration (nAMD). Several anti-VEGF agents are currently available, but…
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