Colloids and surfaces. B, Biointerfaces
Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy.
Cheng-Lei Li, Feng-Ming Li, Ke-Ke Feng, Yong-Shan Hu, Yi-Fan Tu, Shi-Cheng Tian, Zhen-Hua Liu, Jing-Wei Shao
Published: 202610.1016/j.colsurfb.2026.115420
Abstract
Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxide accumulation, offers a promising strategy to circumvent tumor drug resistance. However, solid tumors exhibit intrinsic resistance to ferroptosis due to elevated anti…
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