Colloids and surfaces. B, BiointerfacesReactive Oxygen SpeciesArthritisRheumatoidMacrophagesSelenium
Selenium nanoparticles efficiently inhibit M1 macrophage polarization by regulating selenoprotein to scavenge ROS in alleviating rheumatoid arthritis.
Xiaoyan Zhong, Yang Yang, Limei Jian, Zhenfeng Cheng, Jun Liu, Yukai Huang, Qidang Huang, Zhengping Huang, Tianwang Li, Xu Chen
Published: 202610.1016/j.colsurfb.2025.115236
Abstract
Excessive reactive oxygen and nitrogen species (RONS) in the rheumatoid arthritis (RA) microenvironment act as key functional signaling molecules that induce M1 polarization of synovial macrophages, leading to an imbalance in the M1/M2 macrophage rat…
Preview only. Read the full abstract at the source