Computer methods and programs in biomedicineHumansProto-Oncogene Proteins c-retThyroid NeoplasmsDeep LearningProto-Oncogene Mas
A novel multimodal diagnostic framework integrating hyperspectral imaging and deep learning for predicting RET gene mutations in medullary thyroid carcinoma.
Zhenpeng Yang, Peng Su, Yuyang Zhang, Haitao Zheng, Yupeng Deng, Xiangfeng Lin, Changyuan Ding, Wei Li, Weili Liang, Bin Lv
Published: 202610.1016/j.cmpb.2025.109207
Abstract
BACKGROUND AND OBJECTIVE: Medullary thyroid carcinoma (MTC) is an aggressive malignancy driven predominantly by activating mutations in the RET proto-oncogene. Conventional genotyping using polymerase chain reaction (PCR) or next-generation sequencin…
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