Cell metabolism
Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue.
Jutta Jalkanen, Jiawei Zhong, Pamela A Nono Nankam, Nayanika Bhalla, Merve Elmastas, Jiaxin Luo, Sophie Weinbrenner, Scott Frendo-Cumbo, Benedek Pesti, William Gourash, Anita Courcoulas, Zinger Yang Loureiro, Arne Dietrich, Jesper Bäckdahl, Anders Thorell
Published: 202610.1016/j.cmet.2025.12.008
Abstract
While it is well established that the cellular composition of white adipose tissue (WAT) varies between depots, the functional relevance of this heterogeneity remains unclear. By combining spatial and single-nucleus RNA sequencing, we provide a compr…
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