Clinical oncology (Royal College of Radiologists (Great Britain))HumansBreast NeoplasmsCyclin-Dependent Kinase 4FemaleCyclin-Dependent Kinase 6
Association Between Dose Reduction of Cyclin-dependent Kinase 4/6 Inhibitors and Survival in Advanced Breast Cancer: A Systematic Review and Meta-analysis.
F Petrelli, A Ghidini, L Dottorini
Published: 202510.1016/j.clon.2025.103950
Abstract
AIMS: The integration of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors into the treatment regimen for advanced breast cancer (BC), specifically oestrogen receptor-positive (ER+) subtypes, marks a significant stride in oncological therapy. These inh…
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