Clinical nutrition (Edinburgh, Scotland)AnimalsEnterocolitisNecrotizingEicosapentaenoic AcidFatty Acids
Omega-3 polyunsaturated fatty acids and the eicosapentaenoic acid metabolite 18-hydroxyeicosapentaenoic acid (18-HEPE) attenuate experimental necrotizing enterocolitis.
Hiromu Miyake, Kathryn E Hopperton, Pekka Määttänen, Yuhki Koike, Yong Chen, Bo Li, Carol Lee, Shogo Seo, Philip M Sherman, Richard P Bazinet, Agostino Pierro
Published: 202510.1016/j.clnu.2025.09.015
Abstract
Necrotizing enterocolitis (NEC), a devastating gastrointestinal disease in infants born prematurely, is linked to intestinal inflammation. Maternal intake of omega-3 polyunsaturated fatty acids (PUFAs) has been reported as protective against inflamma…
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