Clinical lung cancerHumansMaleFemaleEtoposideAged
A Phase II Study of Accelerated Hyperfractionated Thoracic Radiotherapy With Dose Escalation to 54 Gy With Concurrent Cisplatin and Etoposide for Limited-Stage Small-Cell Lung Cancer: Long-Term Results at a Single Institution.
Kanji Matsuura, Ritsuko Komaki, Miho Kono, Tsuyoshi Kudo, Ayaka Ono, Tsubasa Kameoka, Ikumi Shintani, Hayate Kusaba, Atsushi Kawakubo, Yasuharu Ando, Kiyoto Nishihara, Yasuo Iwamoto, Hiroyasu Shoda, Tsuyoshi Katsuta, Masayuki Kagemoto
Published: 202510.1016/j.cllc.2025.09.003
Abstract
PURPOSE: The combination of 45 Gy accelerated hyperfractionated thoracic radiotherapy (AHF-TRT) and concurrent chemotherapy is the standard treatment for limited-stage small-cell lung cancer (LS-SCLC). However, the optimal dose and fractionation rema…
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