Clinical therapeuticsAdultFemaleHumansMaleMiddle Aged
Evaluation of Rusfertide, a Hepcidin Mimetic, on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover Thorough QT Study in Healthy Participants.
Nishit B Modi, Phillip Dinh, Hongqi Xue, Borje Darpo
Published: 202510.1016/j.clinthera.2025.09.002
Abstract
PURPOSE: Rusfertide, a hepcidin mimetic, is in clinical development for the treatment of polycythemia vera. This study evaluated the effect of rusfertide on cardiac repolarization. METHODS: A positive-controlled, randomized, double-blind, crossover s…
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