Clinical therapeuticsHumansUnited StatesAdverse Drug Reaction Reporting SystemsPharmacovigilanceMale
Real-world Hepatobiliary Toxicity After Bispecific T-Cell Engager Therapy: A 10-Year Disproportionality Analysis of the Food and Drug Administration Adverse Event Reporting System and the World Health Organization's Global Individual Case Safety Report Database.
Rong Hu, Junyi Shen, Peng Luo, Hui Zhang, Yingyi He
Published: 202510.1016/j.clinthera.2025.09.001
Abstract
PURPOSE: Relapsed/refractory hematological malignancies increasingly utilize bispecific T-cell engagers (BiTEs), yet their postmarketing hepatobiliary toxicity profiles remain inadequately characterized. This study aimed to bridge this knowledge gap…
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