Clinical biochemistryHumansFluorescent DyesImmunoglobulin Light ChainsBlood Protein ElectrophoresisLimit of Detection
A novel fluorescent-labeled serum protein electrophoresis method for detection of monoclonal free light chains in serum.
Gaoyang Pang, Xiaojun Kang, Yan Li, Xiaojuan Zhang, Huijun Ren
Published: 202610.1016/j.clinbiochem.2025.111067
Abstract
BACKGROUND: Current guidelines recommend a combination of serum protein electrophoresis (SPE), immunofixation electrophoresis (IFE), and serum free light chain (FLC) assays for monoclonal immunoglobulin (M-protein) screening. However, the high cost o…
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