Clinical immunology (Orlando, Fla.)HumansDiabetes MellitusType 1CD8-Positive T-LymphocytesMale
Single-cell dissection of CD8+ T cell-driven immune dysregulation in type 1 diabetes mellitus: Mechanistic links to diabetic foot pathogenesis.
Pengbo Yang, Huhe Bao, Guanwen Sun, Yaxing Zhang
Published: 202610.1016/j.clim.2025.110646
Abstract
BACKGROUND: Type 1 diabetes (T1DM) is characterized by autoimmune destruction of pancreatic β-cells and systemic immune dysregulation, yet the cellular networks driving disease progression and their potential link to diabetic complications remain unc…
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