Chinese journal of natural medicinesAnimalsReceptor-Interacting Protein Serine-Threonine KinasesNecroptosisProtein KinasesHydrolyzable Tannins
Discovery based on SPR drug chip that corilagin alleviates acute lung injury in mice by inhibiting necroptosis through targeting RIPK1/RIPK3/MLKL pathway.
Jiezhou Ye, Yuanting Huang, Senquan Wu, Liangli Hong
Published: 202510.1016/j.cjnm.2025.100014
Abstract
Necroptosis, a necrotic form of regulated cell death, plays a crucial role in various tissues and disorders, including sepsis. This process occurs primarily through a caspase-independent mechanism mediated by receptor-interacting protein kinase 1 (RI…
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