Cell host & microbeInfluenza A VirusH5N1 SubtypeNeuraminidaseCross ReactionsHumans
Evolution of antibody cross-reactivity to influenza H5N1 neuraminidase from an N2-specific germline.
Huibin Lv, Yang Wei Huan, Qi Wen Teo, Chunke Chen, Tossapol Pholcharee, Akshita B Gopal, Madison R Ardagh, Jessica J Huang, Ruipeng Lei, Xin Chen, Yuanxin Sun, Yun Sang Tang, Arjun Mehta, Mateusz Szlembarski, Kevin J Mao
Published: 202510.1016/j.chom.2025.09.015
Abstract
The ongoing spread of highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus in animals and its occasional spillover to humans have raised concerns about a potential H5N1 pandemic. Although recent studies have shown that pre-existing human antib…
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