Cell chemical biologyAnimalsAutophagyMuscleSkeletalMice
Lactylation of mTOR enhances autophagy in skeletal muscle during exercise.
Yan Li, Lamei Xue, Feijie Wang, Yu Wang, Yujie Sun, Zhoumin Niu, Shengnan Liu, Ying Yan, Siyi Shen, Kuiliang Zhang, Chenzhipeng Nie, Mingcong Fan, Mei Ma, Yuting Wu, Binrui Yang
Published: 202510.1016/j.chembiol.2025.10.007
Abstract
Emerging evidence suggests that autophagy is activated during exercise, mediating the benefits of exercise. However, the molecular mechanisms underlying the regulation of skeletal muscle autophagy during exercise are incompletely understood. Here, we…
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