Cell systemsIntrinsically Disordered ProteinsProtein BindingBinding SitesComputational BiologyDeep Learning
Disobind: A sequence-based, partner-dependent contact map and interface residue predictor for intrinsically disordered regions.
Kartik Majila, Varun Ullanat, Shruthi Viswanath
Published: 202610.1016/j.cels.2025.101486
Abstract
Intrinsically disordered proteins or regions (IDPs or IDRs) adopt diverse binding modes with different partners, ranging from coupled folding and binding to fuzzy binding and fully disordered binding. Characterizing IDR interfaces is challenging both…
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