Cell reports
Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia.
Liam Clayfield, Divya Malik, Jessica Whittle, Jingru Xu, Renaud Mevel, Muhammad Z H Fadlullah, Rahima Patel, Martyna Szpakowska, Muhammad A Maqbool, Michael Jones, Michael Lie-A-Ling, Andy Chevigne, Jerome Paggetti, Etienne Moussay, Syed Murtuza Baker
Published: 202610.1016/j.celrep.2025.116875
Abstract
Acute myeloid leukemia (AML) is a heterogeneous malignancy driven by abnormal transcriptional programs that block myeloid differentiation and sustain self-renewal. Despite treatment advances over the last 30 years, refractory responses remain common,…
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