Cell reports
Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle.
Xiangyu Zhang, Xiangyi Zeng, Yujun Wu, Xiaoyi Liu, Xu Lin, Hao Wang, Yisi Liu, Luyuan Kang, Zhenyu Wang, Dongdong Lu, Xiaomei Liu, Guanhong Yue, Tengfei Lv, Shiyu Tao, Jinbiao Zhao
Published: 202610.1016/j.celrep.2025.116869
Abstract
Ulcerative colitis (UC) is characterized by intestinal inflammation, barrier dysfunction, and dysbiosis, with limited treatment options. Here, we demonstrate that Lactobacillus delbrueckii is commonly reduced in low-birth-weight piglets, dextran sulf…
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