Cell reports
Cancer-associated fibroblast-derived extracellular vesicles deliver ATP6V1C1 to promote lung adenocarcinoma metastasis via the ID1-IGFBP3 axis.
Xuanming Chen, Jue Li, Cheng Shen, Chunxiu Xiao, Siqi Li, Qiyi Feng, Shuwen Xiao, Jingyao Chen, Manyu Zhao, Siyang Song, Jialong Li, Yuhang Kong, Panwen Tian, Guowei Che, Weimin Li
Published: 202610.1016/j.celrep.2025.116851
Abstract
Cancer-associated fibroblast (CAF)-derived extracellular vesicles (EVs) mediate lung adenocarcinoma (LUAD) progression, but the role of their protein cargo remains poorly defined. Through quantitative proteomic profiling of EVs from patient-derived C…
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