Cell reports
N(6)-methyladenosine modification of RNA is regulated by senataxin and E6 to control HPV replication.
Conor W Templeton, Laimonis A Laimins
Published: 202610.1016/j.celrep.2025.116828
Abstract
The levels of N6-methyladenosine (m6A)-modified RNAs are reduced within cells with high-risk human papillomaviruses (HPVs) in comparison to normal cells. These reduced m6A levels stabilize RNA:DNA hybrids (R-loops), whose regulation is critical for v…
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