Cell reports
Cryo-EM structures of antibodies elicited by germline-targeting HIV MPER epitope scaffolds.
Jiachen Huang, Olivia M Swanson, Kimmo Rantalainen, Monica L Fernández-Quintero, Johannes R Loeffler, Ryan Tingle, Erik Georgeson, Nicole Phelps, Gabriel Ozorowski, Torben Schiffner, William R Schief, Andrew B Ward
Published: 202610.1016/j.celrep.2025.116818
Abstract
Applying cryoelectron microscopy (cryo-EM) to small protein complexes is usually challenging due to their lack of features for particle alignment. Here, we characterized antibody responses to 21 kDa human immunodeficiency virus (HIV) membrane-proxima…
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