Cell reports
Cell-type-selective synaptogenesis during the development of layer 6 corticothalamic neuron connectivity in the mammalian neocortex.
Alan Y Gutman-Wei, Sriram Sudarsanam, Alec G Cabalinan, Naseer Shahid, Anny Shi, Luis E Guzman-Clavel, Sophia M Spindler-Krage, Amit Agarwal, Alex L Kolodkin, Solange P Brown
Published: 202610.1016/j.celrep.2025.116792
Abstract
The function of the mammalian neocortex relies on the timing of axon extension and establishment of cell-type-biased patterns of excitatory synaptic connections. A subtype of excitatory neurons, layer 6 corticothalamic neurons (L6CThNs), ultimately e…
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