Cell reports
A synthetic biology toolkit for the plasmid-dependent and thermophilic methylotroph Bacillus methanolicus.
Pan Liu, Qianqian Yuan, Xueting Yang, Qian Wang, Tao Chang, Yaning Bi, Peng Wu, Tong Zhang, Jinxing Yang, Shiting Guo, Chaoyou Xue, Zhaojuan Zheng, Bo Xin, Hongwu Ma, Yu Wang
Published: 202510.1016/j.celrep.2025.116788
Abstract
Bacillus methanolicus, a unique plasmid-dependent and thermophilic methylotroph, is an ideal chassis for one-carbon (C1) biomanufacturing. Despite its evolutionary uniqueness and industrial promise, the synthetic biology toolkit remains limited in co…
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