Cell reports
MAVS signaling exacerbates chondrocytes extracellular matrix degradation in osteoarthritis.
Hanli Guo, Minghui Sun, Mengdie Tao, Juanjuan Zhu, Yulu Song, Saihua Chen, Zhaoxi Guo, Xiang Zhang, Fajian Hou, Chunmeng Sun, Xiaonan Ma, Haiyang Hu, Ze Hong, Chen Wang
Published: 202610.1016/j.celrep.2025.116778
Abstract
Osteoarthritis (OA) is a prevalent age-related joint disorder with limited treatment options. Chronic activation of the innate immune response in chondrocytes plays a key role in OA progression. However, the underlying mechanisms remain incompletely…
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