Cell reports
A ribosome-bound pseudoknot in the HCV coding region stimulates viral growth by tuning viral translation.
Han Wan, Harim Jang, Ling Xu, Kyrillos S Abdallah, Wendy V Gilbert, Anna Marie Pyle
Published: 202510.1016/j.celrep.2025.116739
Abstract
Recent studies have uncovered a number of functional RNA structures in RNA viruses, yet their regulatory roles remain poorly understood. Here, using an unbiased proteomic approach alongside targeted biochemical assays, we investigate a previously unc…
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