Cell reports
Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury.
Taisuke Mochida, Naoko Fujimoto, Makoto Asahina, Shinya Asano, Shinsuke Araki, Naoto Inukai, Akitsu Hotta
Published: 202510.1016/j.celrep.2025.116695
Abstract
Muscle satellite cells are essential for skeletal muscle regeneration and represent an attractive therapeutic target for gene delivery in Duchenne muscular dystrophy (DMD). However, efficient in vivo transduction of these cells has remained challengi…
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