Cell reportsAnimalsThymus GlandStromal CellsMiceInbred C57BL
Coordinated changes in stromal and hematopoietic cells that define the perinatal to juvenile transition in the mouse thymus.
Anusha Vasudev, Colin R Moore, Aparna Calindi, Seung Woo Kang, Bryan R Helm, Jayashree Srinivasan, Siddhartha Shah, Erin Baker, Ruiting Zong, Nandini Singarapu, Scott Casey, Andrew N Macintyre, Ken S Lau, Laura P Hale, Qi Liu
Published: 202510.1016/j.celrep.2025.116677
Abstract
Perinatal T cells have distinctive phenotypes and functions that may be due in part to age-associated features of stromal cells in the perinatal thymus. We identify age-associated changes in mouse thymic epithelial cells, mesenchyme, endothelium, and…
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