Cell reportsAnimalsCalcitonin Gene-Related PeptideAdipocytesWhiteMice
Sensory-neuron-derived CGRPα controls white adipocyte differentiation and tissue plasticity.
Kyle D Dumont, Saba Heydari Seradj, Yu Wang, Shanshan Liu, Igor Cervenka, Chao Wu, Paulo R Jannig, Margareta Porsmyr-Palmertz, Gerard Baiges-Gaya, Xun Huang, Carina Nihlen, José M Dias, Simona S Skiotyte, Stine Marie Præstholm, Dawn Wilbert
Published: 202510.1016/j.celrep.2025.116613
Abstract
Communication between the brain and adipose tissue is mediated in part by the peripheral nervous system. The sympathetic branch transmits lipolytic and thermogenic signals toward adipose tissue, while sensory nerves relay information to the central n…
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