Cell reportsHumansTaurineMembrane Transport ProteinsMembrane GlycoproteinsSubstrate Specificity
Structural determination of the human taurine transporter TauT reveals the mechanism of substrate and inhibitor recognition.
Yishuo Lu, Dian Ding, Hongyi Chen, Peijun Jiang, Juan Luo, Hui Shan, Guangxi Wang, Jianyuan Luo, Yuxin Yin
Published: 202510.1016/j.celrep.2025.116591
Abstract
Taurine, a sulfur-containing amino acid, is vital for human health because of its antioxidant, anti-inflammatory, and osmoregulatory properties. Its homeostasis is maintained by the Na+/Cl--dependent taurine transporter (TauT). Here, we present five…
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